Article
Reemergence and amplification of tuberculosis in the Canadian arctic.
The Journal of infectious diseases - 15 Jun 2015
Lee Robyn S, Radomski Nicolas, Proulx Jean-Francois, Manry Jeremy, McIntosh Fiona, Desjardins Francine, Soualhine Hafid, Domenech Pilar, Reed Michael B, Menzies Dick, Behr Marcel A
Abstract excerpt
BACKGROUND: Between November 2011 and November 2012, a Canadian village of 933 persons had 50 culture-positive cases of tuberculosis, with 49 sharing the same genotype. METHODS: We performed Illumina-based whole-genome sequencing on Mycobacterium tuberculosis isolates from this village, during and before the outbreak. Phylogenetic trees were generated using the maximum likelihood method. RESULTS: Three distinct...
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