Article
Comparison of routine field epidemiology and whole genome sequencing to identify tuberculosis transmission in a remote setting.
Epidemiology and infection - 4 Feb 2020
Guthrie J L, Strudwick L, Roberts B, Allen M, McFadzen J, Roth D, Jorgensen D, Rodrigues M, Tang P, Hanley B, Johnston J, Cook V J, Gardy J L
Abstract excerpt
Yukon Territory (YT) is a remote region in northern Canada with ongoing spread of tuberculosis (TB). To explore the utility of whole genome sequencing (WGS) for TB surveillance and monitoring in a setting with detailed contact tracing and interview data, we used a mixed-methods approach. Our analysis included all culture-confirmed cases in YT (2005-2014) and incorporated data from 24-locus Mycobacterial...
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