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Article

Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients.

Hepatology (Baltimore, Md.) - 1 Mar 2015

Meissner Eric G, Lee Yu-Jin, Osinusi Anu, Sims Zayani, Qin Jing, Sturdevant Dan, McHutchison John, Subramanian Mani, Sampson Maureen, Naggie Susanna, Patel Keyur, Remaley Alan T, Masur Henry, Kottilil Shyam

Abstract excerpt

UNLABELLED: Hepatitis C virus (HCV) modulates intrahepatic cholesterol biosynthetic pathways to promote viral replication. Chronic HCV infection is associated with altered metabolism, including dyslipidemia and insulin resistance (IR), which contributes to disease progression and influences response to therapy. To further understand the impact of HCV infection on host metabolism, we examined changes in serum...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lipoproteins, LDL

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Share to Uridine Monophosphate

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Source

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Identifiers

PMID: 25203718
DOI: 10.1002/hep.27424
PMCID: PMC4340816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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