Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C Virus

30 Aug 2007

Abstract excerpt

Hepatitis C virus (HCV), a single-stranded positive-sense RNA virus of the Flaviviridae family, infects more than 170 million people worldwide and is the leading cause of liver failure in the United States. A unique feature of HCV is that the viral life cycle depends on cholesterol metabolism in host cells. This review summarizes the cholesterol metabolic pathways that are required for the replication, secretion,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to HIV/AIDS drug development and treatment
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17784784
DOI: 10.1371/journal.ppat.0030108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C VirusPMID 17784784Read ↗

Modulation of host lipid metabolism by hepatitis C virus: Role of new therapies.Semantic proximity Read ↗

Hepatitis C Virus Life Cycle and Lipid MetabolismSemantic proximity Read ↗

The roles of different microRNAs in the regulation of cholesterol in viral hepatitisSemantic proximity Read ↗

The cell biology of hepatitis C virus (HCV) lipid addiction: molecular mechanisms and its potential importance in the clinic.Semantic proximity Read ↗

[Host cholesterol biosynthesis as a potential target for anti-hepatitis C virus strategies].Semantic proximity Read ↗

Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C virusesSemantic proximity Read ↗

Exploitation of Lipid Components by Viral and Host Proteins for Hepatitis C Virus InfectionSemantic proximity Read ↗

Whole Lotta Lipids—From HCV RNA Replication to the Mature Viral ParticleSemantic proximity Read ↗

Hepatitis C virus—biology, host evasion strategies, and promising new therapies on the horizonSemantic proximity Read ↗

Interplay between hepatitis C virus and lipid metabolism during virus entry and assemblySemantic proximity Read ↗

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus InfectionSemantic proximity Read ↗

Lipid Metabolite Profiling Identifies Desmosterol Metabolism as a New Antiviral Target for Hepatitis C VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.