Article
Application of Adaptive Evolution to Improve the Stability of Bacteriophages during Storage.
Viruses - 9 Apr 2020
Kering Kelvin K, Zhang Xiaoxu, Nyaruaba Raphael, Yu Junping, Wei Hongping
Abstract excerpt
Phage stability is important for the successful application of bacteriophages as alternative antibacterial agents. Considering that temperature is a critical factor in phage stability, this study aimed to explore the possibility of improving long-term phage stability through adaptive evolution to elevated temperature. Evolution of three wild-type ancestral phages (Myoviridae phage Wc4 and Podoviridae phages CX5...
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