Article
Enhancement of bacteriophage λ stability using a λQ-S- mutant in the continuous culture of Escherichia coli.
Bioprocess and biosystems engineering - 1 Nov 2010
Oh Jeong Seok, Choi Shin Sik, Park Tai Hyun
Abstract excerpt
In this study, we used a bacteriophage λQ⁻S⁻ mutant that increased the stability of recombinant Escherichia coli during continuous culture. The operation was conducted in two stages: the first stage was carried out to promote cell growth, and the second stage was performed for product formation. The productivity of recombinant proteins depends on the substrate concentration of the fresh medium supplied to the...
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