Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of known and unknown genes associated with mitral valve prolapse using an exome slice methodology.

Journal of medical genetics - 1 Dec 2020

van Wijngaarden Aniek L, Hiemstra Yasmine L, Koopmann Tamara T, Ruivenkamp Claudia A L, Aten Emmelien, Schalij Martin J, Bax Jeroen J, Delgado Victoria, Barge-Schaapveld Daniela Q C M, Ajmone Marsan Nina

Abstract excerpt

PURPOSE: Although a familial distribution has been documented, the genetic aetiology of mitral valve prolapse (MVP) is largely unknown, with only four genes identified so far: FLNA, DCHS1, DZIP1 and PLD1. The aim of this study was to evaluate the genetic yield in known causative genes and to identify possible novel genes associated with MVP using a heart gene panel based on exome sequencing. METHODS: Patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Myosins
Share to Cardiomyopathies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Connectin

Share to Desmoplakins

Share to Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

Share to Mitral Valve Prolapse

Share to Myosin Heavy Chains

Share to Potassium Channels

Source

Identifiers

PMID: 32277046
DOI: 10.1136/jmedgenet-2019-106715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of known and unknown genes associated with mitral valve prolapse using an exome slice methodology.PMID 32277046Read ↗

Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse.Semantic proximity Read ↗

Genetics of syndromic and non-syndromic mitral valve prolapse.Semantic proximity Read ↗

Genetic background of mitral valve prolapse.Semantic proximity Read ↗

Mutation in mitral valve prolapse susceptible gene DCHS1 causes familial mitral annular disjunction.Semantic proximity Read ↗

Genome-wide association meta-analysis supports genes involved in valve and cardiac development to associate with mitral valve prolapseSemantic proximity Read ↗

Utility of genetic screening for the prediction of severe arrhythmic outcomes in mitral valve prolapseSemantic proximity Read ↗

Mutations in DCHS1 cause mitral valve prolapse.Semantic proximity Read ↗

Deleterious variants in DCHS1 are prevalent in sporadic cases of mitral valve prolapse.Semantic proximity Read ↗

Genetic Architecture and Myocardial Fibrotic Remodeling in Mitral Valve ProlapseSemantic proximity Read ↗

Floppy mitral valve/mitral valve prolapse: A complex entity with multiple genotypes and phenotypes.Semantic proximity Read ↗

Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapseSemantic proximity Read ↗

New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.