Article

Mapping the daily rhythmic transcriptome in the diabetic retina

2023-05-30

Abstract excerpt

Retinal function shows marked changes from day to night. Yet, clinical diagnosis, treatments, and experimental sampling occur during the day, leaving a significant gap in our understanding of the pathobiology occurring at night. While there is evidence that diabetes disrupts the circadian system that optimizes our physiology to the environmental light/dark cycle, the impact of such disruption is not well understoo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 37ccdc88-4949-5740-9f13-f0ca4cb14399
DOI: 10.1101/2023.05.27.542572

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mapping the daily rhythmic transcriptome in the diabetic retinaDOI 10.1101/2023.05.27.542572Read

Identification of key genes modules linking diabetic retinopathy and circadian rhythmSemantic proximity Read

Circadian variation of the pancreatic islet transcriptomeSemantic proximity Read

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptomeSemantic proximity Read

Long noncoding RNAs and metabolic memory associated with continued progression of diabetic retinopathySemantic proximity Read

Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic RetinaSemantic proximity Read

Transcriptomic comparison of the retina in two mouse models of diabetesSemantic proximity Read

From mice to humans: Cross-species transcriptomics analysis to uncover distinct mechanisms of Diabetic Retinopathy (DR)Semantic proximity Read

Evidence for conservation of primordial ∼12-hour ultradian gene programs in humans under free-living conditionsSemantic proximity Read

Comparative Analysis of Vertebrate Diurnal/Circadian TranscriptomesSemantic proximity Read

Circadian Regulation of Gene Expression and Metabolism in the LiverSemantic proximity Read

Overlap of expression and alignment of diurnal and circadian rhythmicity in the human blood transcriptome with organ and tissue specific rhythmicity in a non-human primateSemantic proximity Read

Multi-Modal Proteomic Analysis of Retinal Protein Expression Alterations in a Rat Model of Diabetic RetinopathySemantic proximity Read