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Article

Noninvasive prenatal determination of twin zygosity by maternal plasma DNA analysis.

Clinical chemistry - 1 Feb 2013

Qu James Z Z, Leung Tak Y, Jiang Peiyong, Liao Gary J W, Cheng Yvonne K Y, Sun Hao, Chiu Rossa W K, Chan K C Allen, Lo Y M Dennis

Abstract excerpt

BACKGROUND: The current methods for distinguishing the zygosities of twins include ultrasound scanning, which is nondefinitive, and amniocentesis, which is invasive. We explored the use of massively parallel sequencing of maternal plasma DNA for the noninvasive prenatal assessment of the zygosities of twin pregnancies. METHODS: Plasma DNA was extracted from blood collected from 8 women pregnant with twins. Target...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23115054
DOI: 10.1373/clinchem.2012.194068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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