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Article

Noninvasive Evaluation of Fetal Zygosity in Twin Pregnancies Involving a Binary Analysis of Single-Nucleotide Polymorphisms.

The Journal of molecular diagnostics : JMD - 1 Sept 2023

Wang Yanlin, Qiu Xiang, Chen Songchang, Pan Dong, Hua Renyi, Li Shuyuan, Chen Yiyao, Pan Nina, Cai Xiaoqiang, Li Jianli, Zhao Xin, Wang Jing, Jing Ruilin, Xiang Guangxin, Zhang Zhiwei, Huang He-Feng, Xu Chenming, Zhang Jinglan

Abstract excerpt

Twin pregnancy constitutes significant risks for maternal and fetal health, which is usually detected by ultrasound examination at early gestation. However, the imaging-based approach may not accurately identify all twins confounded by practical or clinical variables. The analysis of fetal cell-free DNA in noninvasive prenatal screening assays can completement the ultrasound method for twin detection, which...

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PMID: 37599029
DOI: 10.1016/j.jmoldx.2023.06.003

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