Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients.

doi:10.1002/1878-0261.12669

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Article

Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients.

Molecular oncology - 1 May 2020

Schneegans Svenja, Lück Lelia, Besler Katharina, Bluhm Leonie, Stadler Julia-Christina, Staub Janina, Greinert Rüdiger, Volkmer Beate, Kubista Mikael, Gebhardt Christoffer, Sartori Alexander, Irwin Darryl, Serkkola Elina, Af Hällström Taija, Lianidou Evi, Sprenger-Haussels Markus, Hussong Melanie, Mohr Peter, Schneider Stefan W, Shaffer Jonathan, Pantel Klaus, Wikman Harriet

Abstract excerpt

The combination of liquid biomarkers from a single blood tube can provide more comprehensive information on tumor development and progression in cancer patients compared to single analysis. Here, we evaluated whether a combined analysis of circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and circulating cell-free microRNA (miRNA) in total plasma and extracellular vesicles (EV) from the same blood...

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Identifiers

PMID: 32246814
DOI: 10.1002/1878-0261.12669
PMCID: PMC7191195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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