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Article

Miro2 tethers the ER to mitochondria to promote mitochondrial fusion in tobacco leaf epidermal cells.

Communications biology - 3 Apr 2020

White Rhiannon R, Lin Congping, Leaves Ian, Castro Inês G, Metz Jeremy, Bateman Benji C, Botchway Stanley W, Ward Andrew D, Ashwin Peter, Sparkes Imogen

Abstract excerpt

Mitochondria are highly pleomorphic, undergoing rounds of fission and fusion. Mitochondria are essential for energy conversion, with fusion favouring higher energy demand. Unlike fission, the molecular components involved in mitochondrial fusion in plants are unknown. Here, we show a role for the GTPase Miro2 in mitochondria interaction with the ER and its impacts on mitochondria fusion and motility. Mutations in...

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Identifiers

PMID: 32246085
DOI: 10.1038/s42003-020-0872-x
PMCID: PMC7125145

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