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Article

Challenges and opportunities for strain verification by whole-genome sequencing.

Scientific reports - 3 Apr 2020

Gallegos Jenna E, Hayrynen Sergei, Adames Neil R, Peccoud Jean

Abstract excerpt

Laboratory strains, cell lines, and other genetic materials change hands frequently in the life sciences. Despite evidence that such materials are subject to mix-ups, contamination, and accumulation of secondary mutations, verification of strains and samples is not an established part of many experimental workflows. With the plummeting cost of next generation technologies, it is conceivable that whole genome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32245992
DOI: 10.1038/s41598-020-62364-6
PMCID: PMC7125075

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