Article
Hepatitis C virus nonstructural 4B protein modulates sterol regulatory element-binding protein signaling via the AKT pathway.
The Journal of biological chemistry - 3 Apr 2009
Park Chul-Yong, Jun Hyun-Jeong, Wakita Takaji, Cheong Jae Hun, Hwang Soon B
Abstract excerpt
Hepatitis C virus (HCV) infection is often associated with hepatic steatosis and yet the molecular mechanisms of HCV-associated steatosis are poorly understood. Because sterol regulatory element-binding proteins (SREBPs) are the major transcriptional factors in lipogenic gene expression including...
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