Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lifestyle mediates the role of nutrient-sensing pathways in cognitive aging: cellular and epidemiological evidence.

Communications biology - 2 Apr 2020

de Lucia Chiara, Murphy Tytus, Steves Claire J, Dobson Richard J B, Proitsi Petroula, Thuret Sandrine

Abstract excerpt

Aging induces cellular and molecular changes including modification of stem cell pools. In particular, alterations in aging neural stem cells (NSCs) are linked to age-related cognitive decline which can be modulated by lifestyle. Nutrient-sensing pathways provide a molecular basis for the link between lifestyle and cognitive decline. Adopting a back-translation strategy using stem cell biology to inform...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Senescence
Share to Diet, Healthy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, Mediterranean

Share to Energy Intake

Share to Exercise

Share to Neural Stem Cells

Share to Risk Reduction Behavior

Share to Sirtuin 1

Source

Open in PubMed Open full text

Identifiers

PMID: 32242137
DOI: 10.1038/s42003-020-0844-1
PMCID: PMC7118127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lifestyle mediates the role of nutrient-sensing pathways in cognitive aging: cellular and epidemiological evidence.PMID 32242137Read ↗

Sedentary Life Is an Invisible Trap: Molecular, Cellular, and Systemic Reasons to Leave It BehindSemantic proximity Read ↗

Plasma proteomic signatures of cellular aging predict human disease.Semantic proximity Read ↗

Nutrition, the brain and cognitive decline: insights from epigeneticsSemantic proximity Read ↗

Human longevity: Genetics or Lifestyle? It takes two to tangoSemantic proximity Read ↗

SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study.Semantic proximity Read ↗

Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and BehaviorSemantic proximity Read ↗

Alzheimer’s Amyloid-β Accelerates Cell Senescence and Suppresses SIRT1 in Human Neural Stem CellsSemantic proximity Read ↗

An Update on Neuroaging on Earth and in SpaceflightSemantic proximity Read ↗

Neuronal Stem Cells from Late-Onset Alzheimer Patients Show Altered Regulation of Sirtuin 1 Depending on Apolipoprotein E Indicating Disturbed Stem Cell PlasticitySemantic proximity Read ↗

Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behaviorSemantic proximity Read ↗

Aging in the Brain: New Roles of Epigenetics in Cognitive DeclineSemantic proximity Read ↗

Uncovering the Signatures of Cellular Senescence in the Human Dorsolateral Prefrontal CortexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.