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Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior

7 Jan 2002

Abstract excerpt

Multiple molecular, cellular, structural, and functional changes occur in the brain during aging. Neural cells may respond to these changes adaptively, or they may succumb to neurodegenerative cascades that result in disorders such as Alzheimer's and Parkinson's diseases. Multiple mechanisms are employed to maintain the integrity of nerve cell circuits and to facilitate responses to environmental demands and...

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PMID: 12087131
DOI: 10.1152/physrev.00004.2002

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