Article
An Update on Neuroaging on Earth and in Spaceflight
2025-02-06
Abstract excerpt
Over 400 articles on the pathophysiology of brain aging, neuroaging and neurodegeneration were reviewed, with a particular focus on epigenetic mechanisms and numerous non-coding RNAs, in particular microRNAs, the discovery of whose pivotal role in gene regulation was recognized by the 2024 Nobel Prize in Physiology or Medicine. Aging is not a gradual process that can be easily modeled and described. Instead, multi...
Topics
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- Alzheimer's disease research and treatments
- Genetics, Aging, and Longevity in Model Organisms
- Mitochondrial Function and Pathology
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Sirtuins and Resveratrol in Medicine
- Telomeres, Telomerase, and Senescence
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- 6828e7bf-81da-53c4-a639-eda1864cb58e
- DOI
- 10.20944/preprints202502.0493.v1