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Article

Temporal integration of mitogen history in mother cells controls proliferation of daughter cells

2 Apr 2020

Abstract excerpt

How cells monitor mitogen availability Classical experiments indicated that cells sense the mitogens or growth factors that control cell division within a limited window during the cell cycle. Min et al. reexamined this issue with high-throughput live-cell imaging and temporally controlled perturbations to more closely monitor dynamic signal processing. Human epithelial cells in culture integrated the mitogenic...

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PMID: 32241885
DOI: 10.1126/science.aay8241

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