Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A map of protein dynamics during cell-cycle progression and cell-cycle exit

11 Sept 2017

Abstract excerpt

The cell-cycle field has identified the core regulators that drive the cell cycle, but we do not have a clear map of the dynamics of these regulators during cell-cycle progression versus cell-cycle exit. Here we use single-cell time-lapse microscopy of Cyclin-Dependent Kinase 2 (CDK2) activity followed by endpoint immunofluorescence and computational cell synchronization to determine the temporal dynamics of key...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Microtubule and mitosis dynamics
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28892491
DOI: 10.1371/journal.pbio.2003268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A map of protein dynamics during cell-cycle progression and cell-cycle exitPMID 28892491Read ↗

CD8 T lymphocytes redeploy embryonic cell cycle control mechanisms to facilitate rapid cell proliferationSemantic proximity Read ↗

Spatiotemporal dissection of the cell cycle with single-cell proteogenomicsSemantic proximity Read ↗

Basal p21 controls population heterogeneity in cycling and quiescent cell cycle statesSemantic proximity Read ↗

Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activationSemantic proximity Read ↗

High resolution profiling of cell cycle-dependent protein and phosphorylation abundance changes in non-transformed cellsSemantic proximity Read ↗

Low cell number proteomic analysis using in-cell protease digests reveals a robust signature for cell cycle state classificationSemantic proximity Read ↗

Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomicsSemantic proximity Read ↗

Methods and sensors for functional genomic studies of cell-cycle transitions in single cells.Semantic proximity Read ↗

Systematic characterization of cell cycle phase-dependent protein dynamics and pathway activities by high-content microscopy-assisted cell cycle phenotyping.Semantic proximity Read ↗

The Cell Cycle Browser: an interactive tool for visualizing, simulating, and perturbing cell cycle progressionSemantic proximity Read ↗

A deep single cell mass cytometry approach to capture canonical and noncanonical cell cycle statesSemantic proximity Read ↗

Assembly of a Parts List of the Human Mitotic Cell Cycle MachinerySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.