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The complex nature of heterogeneity and its roles in breast cancer biology and therapeutic responsiveness

23 Feb 2023

Abstract excerpt

Heterogeneity is a complex feature of cells and tissues with many interacting components. Depending on the nature of the research context, interacting features of cellular, drug response, genetic, molecular, spatial, temporal, and vascular heterogeneity may be present. We describe the various forms of heterogeneity with examples of their interactions and how they play a role in affecting cellular phenotype and...

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PMID: 36909339
DOI: 10.3389/fendo.2023.1083048

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