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Article

Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis.

Journal of virology - 1 Jun 2020

Dacus Dalton, Cotton Celeste, McCallister Tristan X, Wallace Nicholas A

Abstract excerpt

Beta genus human papillomaviruses (β-HPVs) cause cutaneous squamous cell carcinomas (cSCCs) in a subset of immunocompromised patients. However, β-HPVs are not necessary for tumor maintenance in the general population. Instead, they may destabilize the genome in the early stages of cancer development. Supporting this idea, β-HPV's 8E6 protein attenuates p53 accumulation after failed cytokinesis. This paper offers...

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Share to Cytokinesis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32238586
DOI: 10.1128/JVI.02184-19
PMCID: PMC7307087

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