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Article

Outcome of Core Binding Factor Acute Myeloid Leukemia by Receptor Tyrosine Kinase Mutation.

Clinical lymphoma, myeloma & leukemia - 1 Jul 2020

Alnagar Ahmed A, Mahmoud Asmaa A, El Gammal Mosaad M, Hamdy Naera, Samra Mohamed A

Abstract excerpt

BACKGROUND: Core binding factor acute myeloid leukemia (CBF-AML) encodes 2 recurrent cytogenetic abnormalities, t(8;21) and inv(16), which carries an overall good prognosis. However, some patients will develop a relapse. We sought define the unfavorable group of CBF-AML by analysis of (c-KIT and FLT3-ITD) and to correlate them with treatment outcome. PATIENTS AND METHODS: We performed a prospective study of 70...

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Identifiers

PMID: 32229198
DOI: 10.1016/j.clml.2020.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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