Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The first pancreatic neuroendocrine tumor in Li-Fraumeni syndrome: a case report.

BMC cancer - 30 Mar 2020

Aversa John G, De Abreu Francine Blumental, Yano Sho, Xi Liqiang, Hadley Donald W, Manoli Irini, Raffeld Mark, Sadowski Samira M, Nilubol Naris

Abstract excerpt

BACKGROUND: Li-Fraumeni syndrome is a cancer predisposition syndrome caused by germline TP53 tumor suppressor gene mutations, with no previous association with pancreatic neuroendocrine tumors (PNETs). Here we present the first case of PNET associated with Li-Fraumeni syndrome. CASE PRESENTATION: This is a 43-year-old female who underwent laparoscopic distal pancreatectomy at age 39 for a well-differentiated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, p53
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Heterozygote

Share to Li-Fraumeni Syndrome

Share to Neuroendocrine Tumors

Share to Pancreatic Neoplasms

Share to Pedigree

Source

Open in PubMed Open full text

Identifiers

PMID: 32228502
DOI: 10.1186/s12885-020-06723-6
PMCID: PMC7106707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The first pancreatic neuroendocrine tumor in Li-Fraumeni syndrome: a case report.PMID 32228502Read ↗

Correlation between choroid plexus carcinoma and Li-Fraumeni syndrome: implications of TP53 mutations and management strategies-a case-based narrative review.Semantic proximity Read ↗

Revisiting tumor patterns and penetrance in germline TP53 mutation carriers: temporal phases of Li–Fraumeni syndromeSemantic proximity Read ↗

Brain tumors in Li-Fraumeni syndrome: a commentary and a case of a gliosarcoma patient.Semantic proximity Read ↗

Case Report : Li-Fraumeni Syndrome with Central Nervous System Tumors in Two Siblings.Semantic proximity Read ↗

Molecular insights into malignant progression of atypical choroid plexus papilloma.Semantic proximity Read ↗

Choroid plexus tumors; management, outcome, and association with the Li–Fraumeni syndrome: The Children's Hospital Los Angeles (CHLA) experience, 1991–2010Semantic proximity Read ↗

Pancreatic Cancer Risk and Screening Outcomes in Li-Fraumeni Syndrome.Semantic proximity Read ↗

"Pure" hepatoid tumors of the pancreas harboring CTNNB1 somatic mutations: a new entity among solid pseudopapillary neoplasms.Semantic proximity Read ↗

MULTIPLE NEUROENDOCRINE NEOPLASIA IN A PATIENT WITH TYPE I NEUROFIBROMATOSIS (NF1): REPORT OF A NEW MUTATION (NF1, EXONS 2-30 DELETION) AND LITERATURE REVIEW.Semantic proximity Read ↗

Choroid plexus papillomas: advances in molecular biology and understanding of tumorigenesisSemantic proximity Read ↗

Li-Fraumeni syndrome: multiple distinct brain tumours in two brothers.Semantic proximity Read ↗

High-grade transformation of pancreatic neuroendocrine tumor associated with TP53 mutations: A diagnostic pitfall mimicking neuroendocrine carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.