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Article

"Pure" hepatoid tumors of the pancreas harboring CTNNB1 somatic mutations: a new entity among solid pseudopapillary neoplasms.

Virchows Archiv : an international journal of pathology - 1 Jul 2022

Mattiolo Paola, Mafficini Andrea, Lawlor Rita T, Marchegiani Giovanni, Malleo Giuseppe, Pea Antonio, Salvia Roberto, Piccoli Paola, Sciammarella Concetta, Santonicco Nicola, Parisi Alice, Silvestris Nicola, Milella Michele, Adsay Volkan, Scarpa Aldo, Luchini Claudio

Abstract excerpt

Hepatoid tumors (HTs) represent a rare group of neoplasms that are histologically similar to hepatocellular carcinoma but arise outside the liver. The current World Health Organization classification recognizes the hepatoid morphology of pancreatic tumors only as a possible variant of pancreatic ductal adenocarcinoma (PDAC). Here, we describe two cases of "pure" HT of the pancreas showing common features and...

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Identifiers

PMID: 35359182
DOI: 10.1007/s00428-022-03317-4
PMCID: PMC9226109

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