Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation between choroid plexus carcinoma and Li-Fraumeni syndrome: implications of TP53 mutations and management strategies-a case-based narrative review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Jun 2024

Mallik Dattatraya, Gopal Swaroop, Scalia Gianluca, Umana Giuseppe, Rajeswarie R T, Chaurasia Bipin

Abstract excerpt

BACKGROUND: Choroid plexus carcinomas (CPCs) are rare, aggressive grade 3 tumors of the central nervous system associated with Li-Fraumeni syndrome (LFS) in a notable percentage of cases due to TP53 germline mutations. Understanding the correlation between CPCs and LFS is crucial for tailored management strategies. However, distinguishing CPCs from benign choroid plexus papillomas (CPPs) remains challenging,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TP53 gene

Share to Germ-Line Mutation

Share to Li-Fraumeni Syndrome

Share to Mutation

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 38316675
DOI: 10.1007/s00381-024-06313-y

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation between choroid plexus carcinoma and Li-Fraumeni syndrome: implications of TP53 mutations and management strategies-a case-based narrative review.PMID 38316675Read ↗

An overview of the diagnosis and management of Choroid Plexus tumors.Semantic proximity Read ↗

TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors.Semantic proximity Read ↗

Choroid Plexus Carcinomas With TP53 Germline Mutations: Management and OutcomeSemantic proximity Read ↗

Choroid plexus tumors; management, outcome, and association with the Li–Fraumeni syndrome: The Children's Hospital Los Angeles (CHLA) experience, 1991–2010Semantic proximity Read ↗

Molecular insights into malignant progression of atypical choroid plexus papilloma.Semantic proximity Read ↗

Choroid Plexus Carcinoma in an Adult: Genetic Insights from a Unique Case StudySemantic proximity Read ↗

Choroid plexus papillomas: advances in molecular biology and understanding of tumorigenesisSemantic proximity Read ↗

Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.Semantic proximity Read ↗

Radiation therapy for choroid plexus carcinoma patients with Li-Fraumeni syndrome: advantageous or detrimental?Semantic proximity Read ↗

Clinical challenges of cancer predisposition syndromes with pediatric central nervous system tumors: a single-center study.Semantic proximity Read ↗

The genetic landscape of choroid plexus tumors in children and adults.Semantic proximity Read ↗

Case Report : Li-Fraumeni Syndrome with Central Nervous System Tumors in Two Siblings.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.