Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer.

doi:10.1158/1078-0432.CCR-20-0168

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Article

Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2020

Stopsack Konrad H, Nandakumar Subhiksha, Wibmer Andreas G, Haywood Samuel, Weg Emily S, Barnett Ethan S, Kim Chloe J, Carbone Emily A, Vasselman Samantha E, Nguyen Bastien, Hullings Melanie A, Scher Howard I, Morris Michael J, Solit David B, Schultz Nikolaus, Kantoff Philip W, Abida Wassim

Abstract excerpt

PURPOSE: The genomic underpinning of clinical phenotypes and outcomes in metastatic castration-sensitive prostate cancer is unclear. EXPERIMENTAL DESIGN: In patients with metastatic castration-sensitive prostate cancer at a tertiary referral center, clinical-grade targeted tumor sequencing was performed to quantify tumor DNA copy number alterations and alterations in predefined oncogenic signaling pathways....

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PMID: 32220891
DOI: 10.1158/1078-0432.CCR-20-0168
PMCID: PMC7334067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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