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Genomic correlates of clinical outcome in advanced prostate cancer

6 May 2019

Abstract excerpt

Heterogeneity in the genomic landscape of metastatic prostate cancer has become apparent through several comprehensive profiling efforts, but little is known about the impact of this heterogeneity on clinical outcome. Here, we report comprehensive genomic and transcriptomic analysis of 429 patients with metastatic castration-resistant prostate cancer (mCRPC) linked with longitudinal clinical outcomes, integrating...

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PMID: 31061129
DOI: 10.1073/pnas.1902651116

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