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Cancer subtype classification and modeling by pathway attention and propagation

19 Mar 2020

Abstract excerpt

MOTIVATION: Biological pathway is an important curated knowledge of biological processes. Thus, cancer subtype classification based on pathways will be very useful to understand differences in biological mechanisms among cancer subtypes. However, pathways include only a fraction of the entire gene set, only one-third of human genes in KEGG, and pathways are fragmented. For this reason, there are few computational...

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PMID: 32207514
DOI: 10.1093/bioinformatics/btaa203

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