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Article

Molecular natural history of breast cancer: Leveraging transcriptomics to predict breast cancer progression and aggressiveness.

Cancer medicine - 1 May 2020

Cook Daniel J, Kallus Jonatan, Jörnsten Rebecka, Nielsen Jens

Abstract excerpt

BACKGROUND: Characterizing breast cancer progression and aggressiveness relies on categorical descriptions of tumor stage and grade. Interpreting these categorical descriptions is challenging because stage convolutes the size and spread of the tumor and no consensus exists to define high/low grade tumors. METHODS: We address this challenge of heterogeneity in patient-specific cancer samples by adapting and...

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PMID: 32207233
DOI: 10.1002/cam4.2996
PMCID: PMC7221450

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