The molecular basis of breast cancer pathological phenotypes.

doi:10.1002/path.4847

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Article

The molecular basis of breast cancer pathological phenotypes.

The Journal of pathology - 1 Feb 2017

Heng Yujing J, Lester Susan C, Tse Gary Mk, Factor Rachel E, Allison Kimberly H, Collins Laura C, Chen Yunn-Yi, Jensen Kristin C, Johnson Nicole B, Jeong Jong Cheol, Punjabi Rahi, Shin Sandra J, Singh Kamaljeet, Krings Gregor, Eberhard David A, Tan Puay Hoon, Korski Konstanty, Waldman Frederic M, Gutman David A, Sanders Melinda, Reis-Filho Jorge S, Flanagan Sydney R, Gendoo Deena Ma, Chen Gregory M, Haibe-Kains Benjamin, Ciriello Giovanni, Hoadley Katherine A, Perou Charles M, Beck Andrew H

Abstract excerpt

The histopathological evaluation of morphological features in breast tumours provides prognostic information to guide therapy. Adjunct molecular analyses provide further diagnostic, prognostic and predictive information. However, there is limited knowledge of the molecular basis of morphological phenotypes in invasive breast cancer. This study integrated genomic, transcriptomic and protein data to provide a...

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Identifiers

PMID: 27861902
DOI: 10.1002/path.4847
PMCID: PMC5499709

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