Article
MicroRNA binding site polymorphisms as biomarkers of cancer risk.
Expert review of molecular diagnostics - 1 Sept 2010
Pelletier Cory, Weidhaas Joanne B
Abstract excerpt
MicroRNAs (miRNAs) are well established as global gene regulators and thus, slight alterations in miRNA levels as well as their ability to regulate their targets may cause important cellular changes leading to cancer risk. 3´ untranslated region (UTR) miRNA binding site single nucleotide polymorphisms (SNPs) have added another layer of possible genetic variation involved in the complex process of oncogenesis....
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