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Article

Dissenting degradation: Deubiquitinases in cell cycle and cancer.

Seminars in cancer biology - 1 Dec 2020

Bonacci Thomas, Emanuele Michael J

Abstract excerpt

Since its discovery forty years ago, protein ubiquitination has been an ever-expanding field. Virtually all biological processes are controlled by the post-translational conjugation of ubiquitin onto target proteins. In addition, since ubiquitin controls substrate degradation through the action of hundreds of enzymes, many of which represent attractive therapeutic candidates, harnessing the ubiquitin system to...

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Identifiers

PMID: 32201366
DOI: 10.1016/j.semcancer.2020.03.008
PMCID: PMC7502435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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