Article
Fast and robust sample self-digitization for digital PCR.
Analytica chimica acta - 22 Apr 2020
Cui Xu, Wu Lei, Wu Yin, Zhang Jinghong, Zhao Qiang, Jing Fengxiang, Yi Lin, Li Gang
Abstract excerpt
We present a facile sample partitioning method to enable rapid and low-cost digital PCR (dPCR) assays. By subdividing a high percentage of the sample volume into a large number of equal volume compartments with a self-digitization (SD) chip, this method can achieve a low-waste and high-order sample discretization in a matter of minutes. The SD chip contains a set of parallel microfluidic channels used for sample...
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