Article
Nucleic acid amplification of individual molecules in a microfluidic device.
Analytical chemistry - 1 Jun 2008
Dettloff Roger, Yang Esther, Rulison Aaron, Chow Andrea, Farinas Javier
Abstract excerpt
A microfluidic device was developed that enabled rapid polymerase chain reaction (PCR) analysis of individual DNA molecules. The device combined a means for accessing samples serially from a microtiter plate, channels for assembling eight parallel PCR reactions, and integrated resistive heaters f...
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