Article
Behavioral Effects of Neuronal, Parent-specific Commd1 Knockout in Mice.
Neuroscience - 10 May 2020
Chase Kayla A, Mallari Jazlene E, Tan Yvette, Sittig Laura
Abstract excerpt
In this study we focused on gene expression and behavioral differences in mice with brain-specific Commd1 knockout. Commd1 is an imprinted gene with preferential maternal expression, residing within a larger genomic region previously found to affect sensorimotor gating. In this study, individuals harboring a conditional Commd1 mutant allele were bred with Syn1-Cre animals, paying special attention to the parent...
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