Hypothalamic-pituitary-adrenal axis-related genes and cognition in major mood disorders and schizophrenia: a systematic review.

doi:10.1016/j.pnpbp.2020.109929

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Article

Hypothalamic-pituitary-adrenal axis-related genes and cognition in major mood disorders and schizophrenia: a systematic review.

Progress in neuro-psychopharmacology & biological psychiatry - 13 Jul 2020

Ferrer Alex, Labad Javier, Salvat-Pujol Neus, Monreal José A, Urretavizcaya Mikel, Crespo José M, Menchón José M, Palao Diego, Soria Virginia

Abstract excerpt

Hypothalamic-pituitary-adrenal (HPA) axis dysregulation and cognitive deficits are two well-characterized endophenotypes present in different serious mental illnesses (SMIs), including major depressive disorder, bipolar disorder and schizophrenia. Our aim was to study the influence of genetic and epigenetic variations in HPA axis-related genes on cognitive performance in clinical samples, including patients with...

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PMID: 32197928
DOI: 10.1016/j.pnpbp.2020.109929

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