Article
Pleuropulmonary blastoma type I might arise in congenital pulmonary airway malformation type 4 by acquiring a Dicer 1 mutation.
Virchows Archiv : an international journal of pathology - 1 Sept 2020
Brcic Luka, Fakler Fabian, Eidenhammer Sylvia, Thueringer Andrea, Kashofer Karl, Kulka Janina, Popper Helmut
Abstract excerpt
Congenital pulmonary airway malformation (CPAM) occurs most commonly in infants. It is divided into 5 types. The most common types 1 and 2 are cystic, type 0 presents as bronchial buds without alveolar tissue, most likely corresponding to alveolar dysgenesis, while type 3 is composed of branching bronchioles and appears as a solid lesion. A defect in the epithelial-mesenchymal crosstalk might be the underlying...
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