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Article

Pleuropulmonary blastoma and DICER1-related tumor predisposition: from clinicopathologic observations to clinical trial.

Current opinion in pediatrics - 1 Feb 2025

Nelson Alexander T, Chen Kenneth S, Schultz Kris Ann P

Abstract excerpt

PURPOSE OF REVIEW: Pleuropulmonary blastoma (PPB) is a rare primary lung neoplasm of infancy and childhood. The purpose of this review is to highlight recent developments in our understanding of PPB and research strategies to facilitate future rare cancer research. RECENT FINDINGS: The International PPB/DICER1 Registry has recently assembled the largest-ever cohorts of type I and Ir PPB and type II and III PPB....

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Child
Clinical Trials as Topic
DEAD-box RNA Helicases
Genetic Predisposition to Disease
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ribonuclease III

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Identifiers

PMID: 39699100
DOI: 10.1097/MOP.0000000000001431
PMCID: PMC11661683

Genes

DICER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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