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Article

Serum FGF-21, GDF-15, and blood mtDNA copy number are not biomarkers of Parkinson disease

6 Jan 2020

Abstract excerpt

BACKGROUND: Strong evidence of mitochondrial dysfunction exists for both familial and sporadic Parkinson disease (PD). A simple test, reliably identifying mitochondrial dysfunction, could be important for future stratified medicine trials in PD. We previously undertook a comparison of serum biomarkers in classic mitochondrial diseases and established that serum growth differentiation factor 15 (GDF-15)...

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PMID: 32190419
DOI: 10.1212/cpj.0000000000000702

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