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Article

Plasma Gelsolin Reinforces the Diagnostic Value of FGF-21 and GDF-15 for Mitochondrial Disorders.

International journal of molecular sciences - 15 Jun 2021

Peñas Ana, Fernández-De la Torre Miguel, Laine-Menéndez Sara, Lora David, Illescas María, García-Bartolomé Alberto, Morales-Conejo Montserrat, Arenas Joaquín, Martín Miguel A, Morán María, Domínguez-González Cristina, Ugalde Cristina

Abstract excerpt

Mitochondrial disorders (MD) comprise a group of heterogeneous clinical disorders for which non-invasive diagnosis remains a challenge. Two protein biomarkers have so far emerged for MD detection, FGF-21 and GDF-15, but the identification of additional biomarkers capable of improving their diagnostic accuracy is highly relevant. Previous studies identified Gelsolin as a regulator of cell survival adaptations...

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Identifiers

PMID: 34203775
DOI: 10.3390/ijms22126396
PMCID: PMC8232645

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