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Article

FGF-21 as a Potential Biomarker for Mitochondrial Diseases

15 Jan 2018

Abstract excerpt

The diagnosis of mitochondrial diseases is still challenging due to clinical and genetical heterogeneity. The development of advanced technologies including Whole-Exome- Sequencing (WES) and Whole-Genome-Sequencing (WGS) has led to improvements in genetic diagnosis. However, a reliable biomarker in serum could enhance and ease the diagnosis and indeed reduce the need for muscle biopsy. Several studies suggest...

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PMID: 29332568
DOI: 10.2174/0929867325666180111094336

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