Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparison of current serum biomarkers as diagnostic indicators of mitochondrial diseases

28 Apr 2016

Abstract excerpt

OBJECTIVE: To directly compare the diagnostic utility of growth differentiation factor-15 (GDF-15) with our previous fibroblast growth factor-21 (FGF-21) findings in the same adult mitochondrial disease cohort. METHODS: Serum GDF-15 levels were measured using a quantitative ELISA. Statistical analyses of GDF-15 data were compared with our published FGF-21 findings. RESULTS: Median serum GDF-15 concentrations were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibroblast Growth Factor Research
Share to GDF15 and Related Biomarkers
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27164684
DOI: 10.1212/wnl.0000000000002705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparison of current serum biomarkers as diagnostic indicators of mitochondrial diseasesPMID 27164684Read ↗

Serum fibroblast growth factor 21 and growth differentiation factor 15: Two sensitive biomarkers in the diagnosis of mitochondrial disorders.Semantic proximity Read ↗

Comprehensive analysis of GDF15 as a biomarker in primary mitochondrial myopathiesSemantic proximity Read ↗

FGF-21 as a Potential Biomarker for Mitochondrial DiseasesSemantic proximity Read ↗

Fibroblast growth factor 21 and grow differentiation factor 15 are sensitive biomarkers of mitochondrial diseases due to mitochondrial transfer-RNA mutations and mitochondrial DNA deletions.Semantic proximity Read ↗

Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age‐related disordersSemantic proximity Read ↗

Plasma FGF‐21 and GDF‐15 are elevated in different inherited metabolic diseases and are not diagnostic for mitochondrial disordersSemantic proximity Read ↗

Plasma Gelsolin Reinforces the Diagnostic Value of FGF-21 and GDF-15 for Mitochondrial Disorders.Semantic proximity Read ↗

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders.Semantic proximity Read ↗

Expanding and validating the biomarkers for mitochondrial diseases.Semantic proximity Read ↗

GDF-15, a mitochondrial disease biomarker, is associated with the severity of multiple sclerosisSemantic proximity Read ↗

The Cytokine Growth Differentiation Factor-15 and Skeletal Muscle Health: Portrait of an Emerging Widely Applicable Disease BiomarkerSemantic proximity Read ↗

Serum FGF-21, GDF-15, and blood mtDNA copy number are not biomarkers of Parkinson diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.