Article

Proliferative and quiescent human gastric cancer stem-like cells are associated with differential chemoresistance and patient mortality

2020-10-23

Abstract excerpt

<h4>Objective</h4> Gastric cancer (GC) tumors are highly heterogenous with different subpopulations of epithelial cells. We employed single cell RNA sequencing (scRNA-seq) to dissect the heterogeneity and identified subpopulations of cancer cells with stem-like properties. We further investigated their resistance to oxaliplatin chemotherapy and their contribution to gastric cancer outcome. <h4>Design</h4> We per...

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Literature Corpus work: 0fb30652-aefd-536a-a1fe-17fc7b155eb2
DOI: 10.1101/2020.10.23.351726

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