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Article

Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis

12 Jan 2018

Abstract excerpt

Abstract Gastric cancer is the fifth most common malignancy and the third leading cause of cancer-related deaths worldwide. Chemotherapies against gastric cancer often fail, with cancer recurrence due potentially to the persistence of cancer stem cells. This unique subpopulation of cells in tumors possesses the ability to self-renew and dedifferentiate. These cancer stem cells are critical for initiation,...

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PMID: 29330298
DOI: 10.1158/1541-7786.mcr-17-0393

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