Article
SRF-FOXO1 and SRF-NCOA1 Fusion Genes Delineate a Distinctive Subset of Well-differentiated Rhabdomyosarcoma.
The American journal of surgical pathology - 1 May 2020
Karanian Marie, Pissaloux Daniel, Gomez-Brouchet Anne, Chevenet Carole, Le Loarer François, Fernandez Carla, Minard Veronique, Corradini Nadege, Castex Marie-Pierre, Duc-Gallet Adeline, Blay Jean-Yves, Tirode Franck
Abstract excerpt
Rhabdomyosarcoma (RMS) encompasses a heterogenous collection of tumors in which new groups have recently been identified that improved the World Health Organization (WHO) classification. While performing RNA-sequencing in our routine practice, we identified 3 cases of well-differentiated RMS harboring new fusion genes. We also analyzed these tumors through array-comparative genomic hybridization. Clinically,...
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