Article
Prognostic relevance of a blastic plasmacytoid dendritic cell neoplasm-like immunophenotype in cytogenetically normal acute myeloid leukemia patients.
Leukemia & lymphoma - 1 Jul 2020
Guolo Fabio, Minetto Paola, Clavio Marino, Marcolin Riccardo, Miglino Maurizio, Passannante Monica, Caviglia Fabrizio, Ballerini Filippo, Tedone Elisabetta, Kunkl Annalisa, Mangerini Rosa, Contini Paola, Colombo Nicoletta, Cagnetta Antonia, Cea Michele, Carminati Enrico, Pugliese Girolamo, Gobbi Marco, Lemoli Roberto Massimo
Abstract excerpt
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a poor prognosis myeloid malignancy characterized by an atypical phenotype (CD123+, CD56+, and CD4+). We reported that BPDCN-like phenotype (CD123+ and either CD56+ or CD4+ or both) confers poor prognosis to acute myeloblastic leukemia (AML) patients with mutated NPM1. Here, we evaluated the incidence and the prognostic relevance of BPDCN-like phenotype in...
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