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Article

Genotype-Specific Neutralization of Norovirus Is Mediated by Antibodies Against the Protruding Domain of the Major Capsid Protein.

The Journal of infectious diseases - 1 Apr 2022

Ford-Siltz Lauren A, Wales Samantha, Tohma Kentaro, Gao Yamei, Parra Gabriel I

Abstract excerpt

Human noroviruses are the most common viral agents of acute gastroenteritis. Recently, human intestinal enteroids were shown to be permissive for norovirus infection. We tested their suitability as a system to study norovirus neutralization. Hyperimmune sera raised against virus-like particles (VLPs) representing different genotypes showed highly specific neutralization activity against GII.4 and GII.6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32179892
DOI: 10.1093/infdis/jiaa116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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