Article
Pikachurin Is Partially Involved in the Synaptic Connection Between Donor and Host Cells in Late-Stage rd1 Mice Following Conspecific Photoreceptor Transplantation.
Stem cells and development - 15 Jun 2020
Liang Chen, Chen YingYing, Jiang XiaoShuang, Zou Ming, Yang Zhen, Li HuiFang, Peng LanYa
Abstract excerpt
Photoreceptor transplantation can rescue the retinal function of late-stage rd1 mice. Many studies have used synaptic markers to suggest that there are synaptic connections after transplantation, but how donor and host cells are connected remains unknown. Many molecules are needed for triad ribbon synapse formation in wild-type mice. Among them, pikachurin is an important extracellular matrix protein that bridges...
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