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Article

Fibroblast-specific Stat1 deletion enhances the myofibroblast phenotype during tissue repair.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 Jul 2020

Medley Shayna C, Rathnakar Bharath H, Georgescu Constantin, Wren Jonathan D, Olson Lorin E

Abstract excerpt

Signal transducer and activator of transcription 1 (Stat1) is a ubiquitously expressed latent transcription factor that is activated by many cytokines and growth factors. Global Stat1 knockout mice are prone to chemical-induced lung and liver fibrosis, suggesting roles for Stat1 in tissue repair. However, the importance of Stat1 in fibroblast-mediated and vascular smooth muscle cell (VSMC)-mediated injury...

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Source

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Identifiers

PMID: 32175700
DOI: 10.1111/wrr.12807
PMCID: PMC7321860

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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