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Article

Integration analysis of metabolites and single nucleotide polymorphisms improves the prediction of drug response of celecoxib.

Metabolomics : Official journal of the Metabolomic Society - 14 Mar 2020

Xing Xiaoqing, Ma Pengcheng, Huang Qing, Qi Xiemin, Zou Bingjie, Wei Jun, Tao Lei, Li Lingjun, Zhou Guohua, Song Qinxin

Abstract excerpt

INTRODUCTION: Pharmacogenetics and pharmacometabolomics are the common methods for personalized medicine, either genetic or metabolic biomarkers have limited predictive power for drug response. OBJECTIVES: In order to better predict drug response, the study attempted to integrate genetic and metabolic biomarkers for drug pharmacokinetics prediction. METHODS: The study chose celecoxib as study object, the...

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PMID: 32172350
DOI: 10.1007/s11306-020-01659-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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